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According to lawyers representing victims of actos bladder cancer side effects, takeda knew as early as 2004 that actos may increase the risk of bladder cancer in users, but waited for seven years to issue a warning about this risk, in order to protect billions of dollars in sales of the drug.


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thiazolidinediones, including actos, cause or exacerbate congestive heart failure in some patients.

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in a 24-week, placebo-controlled study, 260 patients with type 2 diabetes were randomized to one of two forced-titration actos treatment groups or a mock titration placebo group.

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patients with rare hereditary problems of galactose intolerance, the lapp deficiency or glucose-galactose malabsorption should not receive this medicine.

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